Now that yesterday's reaction was the kinetic product of the silylation of an enolate I feel it is right to show the opposite where the thermodynamic product is formed. The requirements for this reaction that differ from the previous one is that the base needed here must be a reversible one, which would cause all of the kinetic products to be reformed and converted to the most thermodynamically favorable product. And that base here is HMDS, or hexamethyldisilazane.
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- 11/29/11 - Silyl Enolate Thermodynamic Product
11/29/11 - Silyl Enolate Thermodynamic Product
- Tuesday, November 29, 2011
- Posted in chemistry, enolate, HMDS, organic, silyl enolate, thermodynamic product
- By Paul Crichton
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