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Thursday, January 17, 2013

1/17/2013 - McMurry Coupling



Hello Chemists, I'm sorry that I have been absent for so long on this blog.  This last term posed more difficult than initially anticipated since I also had my recovery to worry about.  But now that I have finished with school I can solely focus on my very frustrating recovery.

For my first reaction of the new year I have decided to look at a coupling reaction that I worked with in my previous semester, McMurry coupling.  This reaction is named after John McMurry, the man who wrote my second year organic chemistry textbook, of which I always reference in those times of a brain blank. This reaction is a technique used to couple two ketone functional groups together to form a bridged olefin across those two molecules.  This is done through the addition of TiCl3 in THF with Zinc and Copper.