3/17/2012 - Barbier and the Grignard Reactions

    And once again I apologize for my prolonged absence from the blog as with my injury it induces pain that lasts for a good period of time, and then it lets off for a couple days, only to drive right back into the pain.  Some of these times, I really can't find it in me to do a blog post even though I have so much free time condemned to me.
    As the organometallic history progressed, in 1899, a man by the name of P. Barbier investigated reactions involving an alkyl halide being used as an addition reaction onto strongly electrophilic points.  These reactions were usually involving using reactants such as: an alkyl halide, Zinc, and followed by an aqueous work up.  He began studies focused on finding other metals that could have similar use in these kinds of reactions.  He concluded that adding Magnesium instead of Zinc consequented in a more efficient addition.  His student Grignard followed up by effectively describing the reaction in more detail resulting in the reaction being named after him and also with winning the Nobel Prize.

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